However, within 5 years the compound was beginning to trend a new wave in steroid abuse in sports with many athletes disregarding the initial prescription guidelines of 5-15mg. The double bond between C1 and C2 of the A cyclohexane ring reduces the androgencity of the compound with a weaker relative binding affinity for the androgen receptor (AR) than testosterone. The addition of a methyl group at the 17α position of the D cyclopentane ring slows First Pass Metabolism in the Liver to allow it to remain in circulation longer than testosterone. Always consult a qualified healthcare professional before starting any supplement, medication, or performance-enhancing substance. Save my name, email, and website in this browser for the next time I comment. While not a licensed health professional, Jim aims to help readers navigate the often-confusing supplement market through honest, evidence-informed reviews.